The major difference between Gildan DryBlend and Heavy Blend lies in their fabric composition and functionality. Gildan DryBlend garments are crafted from a blend of cotton and polyester (typically 50/50), featuring moisture-wicking properties that help keep the wearer cool and dry, making them ideal for activewear or warmer environments. On the other hand, Gildan Heavy Blend also uses a cotton-polyester mix but focuses on a soft, heavier fabric that provides more warmth and durability, catering to those who prioritize comfort and warmth in cooler conditions.